顾宏伟,硕士生导师,中心实验室副主任,南京市中西医结合医院高层次引进人才,南京大学博士后,美国IOWA STATE UNIVERSITY客座副研究员。主要从事中药调控炎症反应的作用机制、非编码RNA调控机制及中药对肿瘤耐药干预机制等研究。已发表SCI论文27篇,累计影响因子达278分;申请专利10项;主持或参与多项国家、部省级及市级基金。
发表文章:已发表SCI论文27篇,总影响因子达278分;其中以第一/通讯发表SCI论文16篇,总影响因子达126分(1区论文2篇,2区论文4篇),IF大于15的2篇,IF大于7的文章3篇。
近5年发表文章:
1. Hongwei Gu Xuwang Cai Xinyang Zhang Jie Luo Xiaoyang Zhang Xiao Hu Wentong Cai Ganwu Li. A previously uncharacterized two-component signaling system in uropathogenic Escherichia coli coordinates protection against host-derived oxidative stress with activation of hemolysin-mediated host cell pyroptosis,Plos Pathogens. 2021(Oct 15;17(10):e1010005. doi: 10.1371/journal.ppat.1010005.) (IF: 7.464)(第一作者);
2. Xiaoyang Zhang Yanfeng Yan Yunxia Lv Xin Li Leiyao Chen Zihui Huang Junbo Zhou Yong Wang Xiaoming Wang Xu Wang Hongwei Gu*. Dendrobium officinale polysaccharides attenuate uropathogenic Escherichia coli (UPEC)-induced pyroptosis in macrophage cells. Biomedicine & Pharmacotherapy. 2022 May 18;151:113098. doi: 10.1016/j.biopha.2022.113098 (IF: 7.419)(通讯作者);
3. Ling Xu# Hongwei Gu# Guimei Zou Hua Yuan Junbo Zhou1. Autotransplantation of a completely developed impacted maxillary canines: a 7-year follow-up case report. J Am Dent Assoc. 2021(Mar 30;S0002-8177(21)00036-2. doi: 10.1016/j.adaj.2021.01.004.)(IF:3.454)(第一作者);
4. Zihui Huang Jiayan Qian Quanyong Jin Fang Liu Guoying Zhang Hongwei Gu Liangjie Fu Yuling Wang XiaoYang Zhang Yang Yu Jiayue Sun. ex
5. Shuo Zhang Xiaolin Sang Dongxia Hou Jinmei Chen Hongwei Gu Yujing ZhangJing Li Darong Yang Haizhen Zhu Xiao Yang Fangyu Wang Chunni Zhang Xi ChenKe Zen Chen-Yu Zhang Zhi Honga. Plant-derived RNAi therapeutics: A strategic inhibitor of HBsAg. Biomaterials. 2019210:83-93. (IF:15.304);
6. Chihao Zhao Zhen Zhou Tianfu Zhang Fenyong Liu Chen-Yu Zhang Ke Zen and Hongwei Gu*. Salmonella small RNA fragment Sal-1 facilitates bacterial survival in infected cells via suppressing iNOS induction in a microRNA manner. Scientific Reports (2017) (DOI:10.1038/s41598-017-17205-4) (IF:4.996) (通讯作者);
7. Xihan Li Zheng Fu Hongwei Liang Yanbo Wang Xian Qi Meng Ding Xinlei Sun Zhen Zhou Ying Huang Hongwei Gu Limin Li Xi Chen Donghai Li Quan Zhao Fenyong Liu Hua WangJin Wang Ke Zen Chen-Yu Zhang.H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2.Cell Research (2018) 28:157-171. (IF:46.297) ;
8. Hongwei Gu Chihao Zhao Tianfu Zhang Hongwei Liang Xiao-Ming Wang Yi Pan Xi Chen Quan Zhao Donghai Li Fenyong Liu Chen-Yu Zhang and Ke Zen. Salmonella produce microRNA-like RNA fragment Sal-1 in the infected cells to facilitate intracellular survival. Scientific Reports (2017) (DOI:10.1038/s41598-017-02669-1)(IF: 4.996) (第一作者);
中华中医药学会/中药实验药理分会委员