龙芳 女，博士，副研究员，学术学位硕士研究生导师。
从事中药药效物质和质量控制研究，目前研究方向：1. 整合多组学手段，聚焦肠道菌群靶标，开展中药降低化疗药物肾毒性和肠毒性的药效物质和作用机制研究；2. 应用色谱-质谱联用技术对硫熏中药特征标志物进行快速发现及专属性检测方法研究。主持国家自然科学基金面上项目和青年项目各1项，江苏省自然科学基金青年基金项目1项，江苏省中医药科技发展计划项目1项，参与国家级、部省级课题6项。发表SCI期刊论文24篇，发表北大中文核心期刊论文7篇。申请中国发明专利2项，已授权专利1项。获江苏省分析测试协会科学技术奖特等奖1项，江苏分析测试科学技术奖一等奖1项，江苏省科协青年会员创新创业大赛二等奖1项。
近五年课题：
[1] 国家自然科学基金面上项目（82374170）：基于“脾为之卫”理论从短链脂肪酸/尿毒素平衡探讨琼玉膏改善顺铂肾毒性的作用机制，2024.01-2027.12，49万元，在研，主持
[2] 江苏省中医药科技发展计划项目（YB2020021）：基于“肠道菌-短链脂肪酸-肾HDAC”途径的琼玉膏缓解顺铂肾毒性机制研究，2021.05-2024.04，5万元，在研，主持
[3] 国家重点研发计划项目（2019YFC1711004）：中药的分子标识研究以及“中药智慧云”信息平台建设课题“常用中药的活性成分（群）辨识研究”，2019.12-2021.12，594万元，结题，参与（课题骨干，排名第3）
[4] 国家自然科学基金面上项目（81873017）：可靶向调控TAMs极化的灵芝酸A化学免疫给药系统用于乳腺癌联合治疗研究，2019.01-2022.12，57万元，结题，参与（排名第4）
[5] 江苏省中医药研究院青年科学研究项目（QNKXYJ202103）：基于整体观的翼首草“祛风通痹”功效质量标志物研究，2021.08-2023.07，5万元，结题，参与（第二负责人）
近五年发表学术论文情况：
[1] Xiao-Ya Zhang# Jin-Di Xu# Yao Wang Cheng-Ying Wu Jing Zhou Hong Shen Ye-Ting Zou Jin-Hao Zhu Shan-Shan Zhou Song-Lin Li* Jun Xu* Fang Long* Comparing steamed and wine-stewed Rehmanniae Radix in terms of Yin-nourishing effects via me
[2] Xi Shi# Fang Long# Cheng-Ying Wu Jing Zhou Hong Shen Shan-Shan Zhou Jin-Di Xu Wei Zhang* Song-Lin Li* Integrating serum pharmacochemistry and network pharmacology to identify chemical markers for quality control of Apocyni Veneti Folium Phytochemical Analysis 2023 34:56-66.
[3] Ye-Ting Zou Jing Zhou Jin-Hao Zhu Cheng-Ying Wu Hong Shen Wei Zhang Shan-Shan Zhou Jin-Di Xu Qian Mao Ye-Qing Zhang Fang Long* Song-Lin Li* Gut microbiota mediates the protective effects of traditional Chinese medicine formula Qiong-Yu-Gao against cisplatin-induced acute kidney injury Microbiology spectrum 2022 10(3): e0075922.
[4] Ye-Ting Zou Jing Zhou Cheng-Ying Wu Wei Zhang Hong Shen Jin-Di Xu Ye-Qing Zhang Fang Long* Song-Lin Li* Protective effects of Poria cocos and its components against cisplatin-induced intestinal injury Journal of Ethnopharmacology 2021 269: 113722.
[5] Ye-Ting Zou # Fang Long# Cheng-Ying Wu Jing Zhou Wei Zhang Jin-Di Xu Ye-Qing Zhang* Song-Lin Li* A dereplication strategy for identifying triterpene acid analogues in Poria cocos by comparing predicted and acquired UPLC-ESI-QTOF-MS/MS data Phytochemical Analysis 2019 30: 292–310.
[6] 张晓亚 徐金娣 许军 邹叶廷 龙芳* 李松林* 整合糖组与代谢组学方法比较蒸制和酒炖熟地黄化学成分 中草药 2021 52(6):1591-1600.
[7] Zhen Zeng Zhe Sun Cheng-Ying Wu Fang Long Hong Shen Jing Zhou* Song-Lin Li* Quality evaluation of Pterocephali Herba through simultaneously quantifying 18 bioactive components by UPLC-TQ-MS/MS analysis Journal of Pharmaceutical and Biomedical Analysis 2024 238:115828.
[8] Hui-Dan Hou# Cheng-Ying Wu# Jing Zhou Fang Long Hong Shen Jin-Di Xu Shan-Shan Zhou Qian Mao Ying-Jie Wei* Song-Lin Li* Accumulation patterns of major bioactive components in two chemotypes of Agastache rugosa during flower development evaluated by GC-QQQ-MS/MS and UPLC-QTOF-MS/MS analyses Industrial Crops & Products 2023 191:115942.
[9] Meng-Fei Guo# Jing Zhou# Huan-Huan Zhang Ping Zhong Jin-Di Xu Shan-Shan Zhou Fang Long He Zhu* Qian Mao* Song-Lin Li* UPLC-QTOF-MS/MS assisted UPLC-TQ-MS/MS strategy to comparatively investigate the rat pharmacokinetics of N-acetyldopamine oligomers derived from Cicadae Periostracum Journal of Chromatography B 2023 1226:123806.
[10] Cheng-Ying Wu Yi-Yin Guo Jing Zhou Fang Long Wei Zhang Hong Shen Jin-Di Xu Shan-Shan Zhou Song-Lin Li* Holistic quality evaluation of Hibisci Mutabilis Folium by integrating UPLC-QTOF-MS/MS chemical profiling and UPLC-TQ-MS/MS quantification approaches Journal of Pharmaceutical and Biomedical Analysis 2022 218:114869.
[11] Hui-Dan Hou# Cheng-Ying Wu# Jing Zhou Jin-Di Xu Fang Long Jin-Hao Zhu Shan-Shan Zhou Wei Zhang Qian Mao Hong Shen Zi-Qi Shi Ying-Jie Wei* Song-Lin Lia* Holistic quality evaluation of commercial Agastache rugosa by multiple chromatographic and chemometric analysis Journal of Pharmaceutical and Biomedical Analysis 2022210:114574.
[12] Ming-Hui Chen Jing Zhou Cheng-Ying Wu Wei Zhang Fang Long Shan-Shan Zhou Jin-Di Xu Jie Wu Ye-Ting Zou Song-Lin Li* Hong Shen* Gut microbiota influenced the xenograft MC38 tumor growth potentially through interfering host lipid and amino acid me
[13] Meng-Fei Guo Huan-Huan Zhang Ping Zhong Jin-Di Xu Shan-Shan Zhou Fang Long Ming Kong Qian Mao* Song-Lin Li* Integrating multi-type component determination and anti-oxidant/-inflammatory assay to evaluate the impact of pre-molting washing on the quality and bioactivity of Cicadae Periostracum Molecules 202227:7683.
[14] Wei Zhang Wei-Wei Tao Jing Zhou Cheng-Ying Wu Fang Long Hong Shen He Zhu Qian Mao Jun Xu* Song-Lin Li* Qi-Nan Wu* Structural analogues in herbal medicine ginseng hit a shared target to achieve cumulative bioactivity Communications Biology 2021 4:549.
[15] He Zhu Hui Liu Jin-Hao Zhu Si-Yu Wang Shan-Shan Zhou Ming Kong Qian Mao Fang Long Zhi-Jun Fang* Song-Lin Li* Efficacy of ginseng and its ingredients as adjuvants to chemotherapy in non-small cell lung cancer Food & Function 2021 12:2225.
[16] Cheng-Ying Wu Jing Zhou Fang Long Wei Zhang Hong Shen He Zhu Jin-Di Xu Song-Lin Li* Similar hypoglycemic effects of glucomannan and its enzyme degraded products from Amorphophallus albus on type 2 diabetes mellitus in mice and potential mechanisms Food & Function 2020 11: 9740–9751.
[17] Jing Zhou# Jie Wu# Cheng-Ying Wu Fang Long Hong Shen Wei Zhang* Song-Lin Li* Herb-drug interaction: A case study of effects and involved mechanisms of cisplatin on the pharmacokinetics of ginsenoside Rb1 in tumor-bearing mice Biomedicine & Pharmacotherapy 2019 110: 95–104.
[18] 沈红 伍城颖 龙芳 周静 周姗姗 许军* 李松林* 从肠道菌群调控角度探讨中药汤剂中多糖组分存在的意义 药学学报 2022 57(12):3480-3486.
[19] 邹叶廷 徐金娣 龙芳 张业清 李松林* 整合UPLC-QTOF-MS/MS全扫描和模拟MRM方法综合评价茯苓乙醇提取物与后续乙酸乙酯萃取物三萜酸类组分化学一致性 药学学报 2019 54(1): 130-137.
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